Inside these cells, AAS can biotransform into various metabolites or bind to their cognate receptor: the androgen receptor. AAS and their metabolites could potentially cause side effects such as acne vulgaris, hypertension, hepatotoxicity, dyslipidemia, testosterone deficiency, erectile dysfunction, gynecomastia, and cardiomyopathy. In which releva
AASs exert their effects by activating androgen receptor (AR) signaling. Quite a few portions of the body are involved due to existence of ARs in lots of tissues [twelve]. At normal physiologic levels of testosterone androgen receptors are saturated as well as the AASs consequences could be a consequence of other mechanisms instead of androgen rece
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